Thesis work, 30 credits - Preclinical Pharmacokinetics and Translation in Obesity Population

We are offering a unique chance to explore how obesity affects drug absorption, distribution, metabolism, and excretion (ADME) in preclinical settings. This project will enhance the translation of findings to clinical applications through cutting-edge pharmacokinetic modeling and simulation. 

About AstraZeneca: 

AstraZeneca is a global, science-led, patient-centred biopharmaceutical company focusing on discovering, developing, and commercialising prescription medicines for some of the world’s most serious diseases. But we’re more than a global leading pharmaceutical company. At AstraZeneca, we're dedicated to being a Great Place to Work and empowering employees to push the boundaries of science and fuel their entrepreneurial spirit.  

About the Opportunity: 

As a Thesis Worker at AstraZeneca, you’ll find an environment that’s full of unique opportunities and exciting challenges. Here, you’ll have the opportunity to pursue your areas of interest whilst equally developing a broad skillset and knowledge base to get the best out of your experience. You’ll be working on meaningful projects to make an impact and deliver real value for our patients and our business. 

Thesis work description:  

Join us on an exciting research journey to explore how obesity influences pharmacokinetics and the translational applications in drug development. This master thesis project aims to fill a critical research gap regarding the effects of obesity and its associated comorbidities on the Absorption, Distribution, Metabolism, and Excretion (ADME) processes. Understanding these effects is crucial for improving the translation of findings from preclinical models to clinical applications. 

Key Objectives:

• Investigate the impact of obesity on pharmacokinetics and pharmacodynamics of various drug modalities. 
• Enhance the understanding of obesity-related modulation of ADME processes. 
• Utilize pharmacokinetic modeling and simulation to analyze both external and in-house data. 

Structure: 

• Duration: Fall term 2025 
• Credits: 30 

Essential Requirements: 

• Enrolled in a master's program within Pharmacy/Biotechnology/Mathematics or another relevant field 

So, what’s next?  

Apply today and take the chance to be part of making a difference, making connections, and gaining the tools and experience to open doors and fulfil your potential. We can´t wait to hear from you!  

We welcome your application as soon as possible, but ahead of the scheduled closing date 13th April 2025. In the event that we identify suitable candidates ahead of the scheduled closing date, we reserve the right to withdraw the vacancy earlier than published.  

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.