Global Brand Director – Respiratory

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Position Summary:

Tozorakimab, a novel high affinity IL-33 antibody that is the first anti-IL-33 antibody suppressing activity of both IL-33red–ST2 and IL-33ox–RAGE/EGFR signaling pathways with potential for differentiated efficacy vs competitors.  

Tozorakimab is being developed by AstraZeneca and is expected to be the leading anti-IL33 therapy with the broadest and most differentiated claim set in class and represents one of the top company priorities within the respiratory TA and the overall portfolio. Tozorakimab is expected to launch in its first indications of COPD and severe viral Lower Respiratory Tract Disease (svLRTD) in 2027.

We are looking for a Lifecycle Management (LCM) Marketing Director to lead commercial lifecycle strategy for Tozorakimab, a first in class respiratory biologic product in late development. This role will join our Respiratory Biologics BioPharmaceutical Commercial team, reporting to the Global Commercial VP of the product. 

This role will lead the development of commercial plans to maximize the potential value of the product to expand the franchise to additional indications beyond COPD and svLRTD. The LCM director will work in collaboration with translational and clinical science to identify prospective opportunities, build patient centric strategic marketing plans and value propositions, advise on development strategy and create compelling business cases for investment decisions. 

This role is expected to champion the product and LCM program and help build a franchise that will maximize long-term value and potential to help patients and health care professionals. The successful candidate will work collaboratively with the commercial and project teams, as well as with regional commercial leaders and our collaboration partner to prepare new opportunities to grow the franchise. We are seeking a candidate with leadership potential who is looking to improve existing skills and develop higher-level capabilities. 

 You will be accountable for the development of the commercial strategy, successful commercial investment decision across LCM indications. You will also play a role in the launch of COPD, leading some commercial efforts and being the global liaison for a given geography.  

You will represent the commercial voice in the GPT (Global Product Team) providing commercial input and contributing to the decision making on future clinical development projects. You will collaborate closely with Medical Affairs, R&D, Clinical Operations, Pricing & Market Access, Regulatory Affairs, Manufacturing and the GPT to ensure on time delivery of the evidence support the asset, to build patient centric marketing plans and value propositions, to advise on new indication strategy and to create a compelling business case for the commercial investment decisions. You will actively participate in the evidence generation team and engage with external stakeholders around the progression of the narrative in alignment with the developing evidence. 

The successful individual will demonstrate strong skills in the areas of strategic thinking, decision making, communication, leadership, problem solving and collaboration. They will also be able to work well with ambiguity, simplify complexity and manage multiple priorities. 

Major Duties and Responsibilities: 

As the global marketing director, you will represent Global and be accountable for: 

• Champion the product and LCM program beyond COPD and svLRTD.  

• Launch of COPD, leading some commercial efforts.  

• Developing LCM commercial strategy and future commercial opportunities. 

• Building a robust business case to support a positive commercial investment decision. 

• Represent the commercial LCM voice within the cross functional global product team. 

• Engaging with the head of brand to ensure a flawless and aligned execution of the strategy and incorporation of evidence.  

Requirements/Qualifications: 

Education:   Bachelor’s degree is required with business degree or scientific expertise as preferred. Master’s degree is desired.  

Experience:  

• A minimum of 10+ years’ experience in healthcare or biopharma industry, with a strong preference for experience in the respiratory therapeutic area, in particular in respiratory disease and/or biologics viral infectious diseases. 

• In-depth understanding of commercial strategy, methodologies and tools (product profiling and positioning, forecasting, pricing & reimbursement, market research techniques, competitive intelligence resources). 

• Thorough ‘hands-on’ knowledge of building TPPs, generating sales forecasts and business cases.  

• Experience of shaping brand strategy whilst the understanding of product profile was incomplete and evolving. 

• Thorough understanding of the drug development process and the need for commercial line of sight throughout. 

• Understanding of future healthcare market challenges including local regulatory DO’s and DON’Ts.  

• Exposure to and track record of effective management of senior decision-making/governance bodies. 

• Proven experience of engaging with and leveraging insights from external customers e.g. KEEs, prescribers, and payors. 

• Preferred: Strong understanding and experience of launching medicines in the US health system 

Special Skills/Abilities:   

• Strong strategic thinking, decision making, and problem solving 

• Strong leadership and influencing skills to ensure a strong commercial focus in R&D projects  

• Proven ability to collaborate across functional boundaries 

• Demonstrated ability to bring ideas to action 

• Strong analytical, organizational and communication skills (written and verbal) required 

• Ability to work with ambiguity and complexity and manage multiple priorities 

The annual base pay for this position ranges from $229,303 to $343,955. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.  In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. ​

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.