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Asset Performance Management (APM) Senior Engineer

Lieu Mount Vernon, Indiana, United States Job ID R-235960 Date de publication 09/23/2025

The AstraZeneca Mt. Vernon site was established in 1972 and is the flagship site delivering innovative, life changing oral solid medicines. At the site we formulate and pack OSD tablets and capsules for over 60+ markets. The Mt Vernon site is complex, the largest AZ production site in the US with over 700+ employees.  We are located in the southwest corner of the state of Indiana, approximately 15 miles from Evansville, Indiana – the third largest city in the state.  The Mt. Vernon site is both collaborative and Inclusive.  We have several employee resource groups (ERGs) onsite that are aimed at promoting, celebrating, and educating employees about diversity, inclusion, philanthropy, networking, etc. Each of these groups provide employees with opportunities for interactive and engaging events and initiatives which enhance professional development and provide opportunities to engage with likeminded co-workers.  

It is important to us that each employee feels welcome to bring their whole self to work every day. Here is a sneak peek of some of “perks” the MTV site offers: on-site fitness center with access to a personal trainer, on-site walking trail, walking desk, on-site basketball court, ping pong, massage chair, lunch & learns, sustainable & ergonomic office working environment, tuition reimbursement, training/ lifelong learning opportunities, book club, dining center with hot meals, snack market, free coffee and hot tea, climate controlled work environment.

Are you ready to make a significant impact on equipment reliability and asset optimization? As an Asset Performance Management (APM) Senior Engineer, you'll be at the heart of driving continuous improvement and innovation at our site. You'll leverage data and technical leadership to enhance asset lifecycle management, collaborating with maintenance, operations, and Lean digital teams to transition towards data-driven maintenance that supports manufacturing excellence.

Accountabilities:
- Serve as a technical lead for reliability methodologies, asset lifecycle management, early equipment management, and condition-based monitoring, partnering with the Reliability & TPM Director to implement and enhance work processes and standards.
- Monitor and analyze equipment performance and reliability data and KPIs from SAP and downtime tracking tools to identify trends and recommend improvements.
- Develop and deliver leadership reporting and insights by tracking asset performance and reliability KPIs, analyzing data to identify issues or improvement opportunities, and supporting cross-area benchmarking.
- Act as a change champion for TPM, reliability, and prescriptive maintenance initiatives by promoting new practices and engaging stakeholders across teams.
- Champion the integration of Prescriptive Maintenance by working with digital, maintenance, and operations teams to implement advanced, data-driven approaches. This includes leveraging real-time and historical equipment data, advanced analytics, AI, and machine learning to predict potential failures and prescribe the most effective corrective actions, making proactive asset management a core site capability.
- Lead or facilitate cross-functional investigations and workshops (e.g., root cause analysis, FMEA, equipment criticality assessments) to solve equipment issues and drive reliability initiatives.
- Champion Early Equipment Management (EEM) for new projects and major upgrades by ensuring reliability and maintainability are considered in equipment selection, design, and installation, and by engaging operators and maintenance teams for input throughout the process.
- Scout and pilot new reliability and maintenance technologies in partnership with digital, LEAN, and maintenance teams to support continuous improvement and innovation.
- Collaborate with TPM facilitators, maintenance, and operations teams to execute criticality analyses, breakdown studies, and reliability projects in line with TPM principles.
- Help develop and optimize preventive and predictive maintenance programs, targeting chronic failures (“bad actors”) through systematic data analysis.
- Support the adoption and effective use of digital tools for asset health monitoring, working closely with Lean digital teams to advance autonomous manufacturing.
- Contribute to spare parts inventory decisions, using data and risk assessments to optimize stock levels and support plant reliability goals.
- Assist in drafting and deploying site reliability procedures, standards, and training materials, helping to upskill operations and maintenance personnel.
- Present findings and recommendations to site leadership, ensuring alignment and support for reliability and performance improvement efforts.
- Ensure compliance with internal/external standards and support audits related to asset management.

Essential Skills/Experience:
- Bachelor’s degree in engineering or related scientific or industrial discipline
- 5+ years of relevant manufacturing experience in a technical position
- Strong analytical and data interpretation skills
- Experience leading technical workshops and reliability investigations
- Solid understanding of maintenance processes
- Effective communicator and influencer in cross-functional teams

Desirable Skills/Experience:
- Advanced degree or certification in reliability or maintenance engineer
- Certification or training in data analytics
- Certification or training in Total Productive Maintenance 
- Experience in pharmaceutical OSD manufacturing or other GMP regulated industries
- Experience with SAP, data historians, and predictive/prescriptive maintenance tools

AstraZeneca offers an environment where your contributions are valued as we strive to improve patient healthcare. With a focus on innovation, we embrace the latest models and technologies to enhance reliability in our processes. Our commitment to quality is unwavering as we certify each batch with a personal stamp of approval. Here, you'll be empowered to make decisions that prioritize patient outcomes while working collaboratively across teams. Join us in our mission to deliver medicines safely and sustainably.

Ready to take on this exciting challenge? Apply now to become part of our dynamic team!

Date Posted

22-Sep-2025

Closing Date

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.



AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

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