Facilities Maintenance Supervisor

Position Summary:

The Facilities Maintenance Supervisor leads maintenance operations to ensure the safe, compliant, and highly reliable performance of critical manufacturing and facility systems supporting cell therapy production in Tarzana, CA. In a Cell Therapy environment, where products are often patient-specific and time-sensitive, this role is critical to maintaining uninterrupted operations, cleanroom conditions, and strict chain-of-identity and chain-of-custody controls Tarzana, CA. The role integrates reliability engineering principles with daily maintenance execution, focusing on eliminating repeat failures, reducing unplanned downtime, and improving asset lifecycle performance in a highly regulated environment governed by FDA expectations and advanced therapies guidelines.

Success in this role requires the ability to:
• Lead teams in a fast paced, patient-centric manufacturing environment
• Balance speed, compliance, and precision
• Anticipate and mitigate risks to critical, often irreplaceable batches
• Drive transition from reactive to predictive maintenance strategies
• Collaborate multi-functionally with Manufacturing, Quality, and Engineering to support 7 days cell therapy operations

Ultimately, the Maintenance Supervisor plays a direct role in ensuring that life-saving therapies reach patients safely, reliably, and on time, by maintaining the integrity and performance of the systems that produce them.

Responsibilities:

• Leadership & Team Management: Manage and mentor maintenance technicians; set clear expectations for safety, quality, and performance; lead daily tier meetings and shift handovers; build a culture of ownership, urgency, and continuous improvement; collaborate with Engineering, Quality, and Operations.

• Maintenance Execution & Compliance: Ensure all activities meet GMP, FDA, and site standards; review and approve complete, accurate work orders; enforce CMMS usage (e.g., SAP); lead aspects of preventive and corrective maintenance and calibrations; maintain inspection readiness and support audits.

• Reliability & Asset Management: Implement reliability‑centered maintenance; investigate failures using RCA and FMEA; improve MTBF and MTTR; identify and resolve “bad actor” equipment; partner on upgrades and lifecycle management.

• Planning & Scheduling: Work with the Maintenance Planner to prioritize and schedule work; secure parts, tools, and permits in advance; validate and refine job plans; increase labor efficiency and minimize reactive work.

• Safety, Health, and Environment (SHE): Enforce LOTO, confined space, and permit systems; conduct safety observations, audits, and incident investigations; lead by example to sustain a zero‑incident culture.

• Continuous Improvement: Remove waste from maintenance processes; increase schedule compliance, PM efficiency, and spare‑parts management performance; lead or participate in Kaizen and Lean initiatives.

• Work Environment: AZ is a cGMP regulated pharmaceutical manufacturing facility. We require your presence on the production floor and occasional off-shift support This may involve gowning for cleanroom environments

Minimum requirements:

• High school diploma/GED required.
  8+ years in industrial facilities maintenance/leadership experience

• 4+ years of leadership experience in a pharmaceutical, biotech, or GMP regulated environment (medical device/food service may be acceptable.)

Desirable:

• Technical diploma/apprenticeship in HVAC orBoiler maintenance.

• Bachelor’s degree in Mechanical engineering or Facilities Management is a plus.

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The annual base salary for this position ranges from $89,874 to $134,812. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles).

Our Benefits:

Benefits offered include:

#celltherapy

Date Posted

03-Apr-2026

Closing Date

19-Apr-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.