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Lieu: Göteborg, Comté de Västra Götaland, Suède
ID de l'offre 13402895
Date de publication: 09/19/2019

AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialisation of prescription medicines for some of the world’s most serious diseases. We're proud to have a unique workplace culture that inspires innovation and collaboration. We believe in the potential of our people and you’ll develop beyond what you thought possible.

The new R&D BioPharmaceuticals organisation brings together research and development teams, from discovery through to late-stage development for Cardiovascular, Renal & Metabolic (CVRM), Respiratory, Inflammatory and Autoimmune (RIA) therapy areas, and opportunistically for Microbial Sciences and Neuroscience.

Our Discovery Sciences team operates from truly state-of-the-art centres spanning the UK, US and Sweden. You’ll work with some of the most knowledgeable technological experts in the industry, all collaborating on high-profile drug discovery projects.

You’ll be in a global pharmaceutical environment but also exposed to strong rigorous academic science. For example, every postdoc has an external academic mentor to ensure we are working and publishing at the highest level in a field. What’s more, you’ll have the support of a leading academic advisor, who’ll provide you with the guidance and knowledge you need to develop your career.

A unique opportunity to join a World Leading Hit Discovery group, working in a multi-disciplinary lab with synthetic and analytical chemists, biologists, programmers and engineers developing catalytic technologies supporting AZ drug discovery projects.

This is an opportunity to work on a joint BBSRC funded project with University of Bristol, UK (Profs Paul Race and Chris Willis) and AstraZeneca on Diels-Alderases.and their application in Drug Discovery Chemistry. The position is based in the AstraZeneca iLAB, Hit Discovery, Discovery Sciences in Gothenburg, Sweden. You'll have responsibility for all aspects of evaluating the potential of DA enzymes as synthetic catalysts for drug discovery.

Education and Experience required:

Essential:

  • PhD in Biochemistry/Synthetic Biology /Biotechnology/ Organic Chemistry
  • Experience of using recombinant enzymes/ whole cells to perform biotransformations
  • Experience with analytical tools e.g. UPLC-MS, GCMS, NMR
  • Molecular biology: cloning, expression, protein purification - experience in a variety of expression systems desirable
  • Track record of work published in good scientific journals

Desirable:

  • Interest in drug discovery/hit finding strategies
  • Interest/experience in using automation/robotics/Tecan/Mosquito/Andrew
  • Interest/experience in high throughput experimentation and data-processing
  • Post-doctoral experience 1-3 years in a related area

Skills and Capabilities required:

  • Strong technical, organisational, interpersonal skills
  • Excellent written and spoken communication skills
  • A genuine interest inpharmaceutical research

This is a 3 year programme.  2 years will be a Fixed Term Contract, with a 1 year extension which will be merit based.  The role will be based in Gothenburg, Sweden, with a competitive salary on offer

To apply for this position, please click the apply link below

Advert opening date – 20th September 2019 / Advert closing date – 21st October 2019

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

Postdoc Fellow - Biocatalysis in Drug Discovery
Domaines scientifiques

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