Scientist

EMPLOYER: AstraZeneca Pharmaceuticals LP

TITLE:   Scientist

LOCATION:   Gaithersburg, MD

HOURS:  Full-Time; Mon-Fri (40 hours/week)

DUTIES:  Analyze datasets and develop methods for optimizing novel conjugation and purification methodologies, including high throughput conjugation and purifications. Perform discovery and optimization of next generation biologics to create biological drug candidates for all key therapeutic areas. Design and perform drug conjugation experiments to support the antibody drug conjugates (ADCs) pipeline and technology development. Use FPLC (fast protein liquid chromatography) and ATKA (affinity chromatography for protein purification) to purify mg to gram scale conjugates using various chromatography techniques. Perform biochemical and biophysical characterization of the ADCs. Present findings.

REQUIREMENTS:  Must have a Bachelor’s degree or foreign equivalent in Biomedical Engineering, Biotechnology, or a related scientific field, plus six (6) years of progressively responsible experience in the job offered, as an Associate Scientist or in a related occupation. Must possess at least six (6) years of progressively responsible experience in all of the following: Providing quality control and assay validation, Developing and optimizing conjugation and purification methodologies, Utilizing analytic methods to characterize conjugates including DLS, SEC, HIC, LC-MS, Assessing Antibody-Drug-Conjugate (ADC) Assay Development, Developing methods to determine and evaluate drug candidates, and Utilizing routine DNA/RNA techniques. In the alternative, employer will accept a Master’s degree or foreign equivalent in Biomedical Engineering, Biotechnology, or a related scientific field, plus four (4) years of experience in the job offered, as an Associate Scientist or in a related occupation. Any combination of education, experience or training is acceptable.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

Click Apply to submit your application. No calls please.  EOE.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.