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Scientist: Microbiome Discovery, Flow Cytometry & in vivo models

Lieu Gaithersburg, Maryland, États-Unis Job ID R-121864 Date de publication 11/01/2021

Scientist, Microbiome Discovery: Flow cytometry and in vivo models
Here at AstraZeneca, you’ll have the opportunity to make a difference in people’s lives every day. As one of the world’s premier biotechnology companies, our mission is centered on delivering life-changing products that advance world health and help fight and cure disease. As a Scientist - Microbial Sciences in Gaithersburg, MD, you’ll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients’ lives. 

The Microbial Sciences group at AstraZeneca is studying the impact of the microbiome on the host immune response. We’re constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. We’re pioneering innovative research and exploring novel pathways through which the microbiome can be used across key therapeutic areas including respiratory, inflammation and autoimmunity, cardiovascular and metabolic disease, and infection and vaccines. We’re industry-leading in immunology, protein engineering, and translational science. We offer a unique and strong collaborative network as part of the AstraZeneca family, as together we explore synergies between small and large molecules.

AstraZeneca has a dynamic environment that fosters collaboration and innovation. We attract top minds, and we nurture and build top talent.

Major responsibilities:
Conduct in vivo/in vitro experiments to assess the impact of the microbiome on mucosal immunology, systemic inflammation and therapeutic efficacy in models spanning cardiovascular, metabolic, and renal disease areas. 

Requirements/ Qualifications:
Scientist: 
• Degree in immunology, cell biology, or related subject
• Relevant experience in the industry (preferred) or academia
• M.S. with 2-5 years additional experience; B.S. with 5-8 years additional experience


Specific skills: 
• Experience working with animals is required and prior experience with the microbiome is highly desired.  
• Broad experience required in immunologic assays (e.g. flow cytometry, single-cell sequencing, ex vivo analysis of immune cell function).  
• Additional experience in higher level in vitro tissue models (organoid or organ on a chip), confocal and fluorescent imaging, and molecular biology would be a plus. 
• Exposure to metabolic, cardiovascular, or renal models is a plus. 
• The candidate must be dedicated to maintaining high laboratory standards with regard to safety and quality and must possess good organization, record keeping, and communication skills.

Job complexity: Must be able to understand, conduct and interpret results of technically challenging experiments with minimum supervision, as part of a matrixed and collaborative team.

Supervision: Initial supervision and training by supervisor/team members, but independence expected in long term.

Next Steps – Apply today!

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity.  If you know someone who would be a great fit, please share this posting with them.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.

AstraZeneca has taken critical steps to protect colleagues, loved ones, and patients from COVID-19 and its variants.  COVID-19 vaccination is required for all US employees, and weekly PCR COVID-19 testing is required for those who are unvaccinated or have an approved accommodation.



AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

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