Health Economics & Payer Evidence (HEPE) Lead

Health Economics & Payer Evidence (HEPE) Lead

Introduction to role:

Are you ready to set the strategic payer evidence direction that turns breakthrough science into patient access? As the HEPE Lead, you will guide how our medicines earn and retain access across the world, partnering closely with clinical, medical evidence, observational research, and payer teams.

You will operate as a forward-looking strategic partner, translating insights into target product profiles and global payer evidence plans that stand up to scrutiny and shape pricing and market access strategies. Do you thrive in complexity and enjoy challenging the status quo to unlock sustainable access? Your leadership will set the pace and standard for how we design, test, and communicate value for patients, payers, and health authorities.

Accountabilities:

You will have a global senior-level leadership role and be responsible for setting the strategic HEPE direction for the compounds you are working on, demonstrating the value of our products to patients, payers and health authorities. You will collaborate with Clinical Development, Medical Evidence Generation, Observational Research, and Payer Teams in designing and implementing innovative HEPE strategies and activities for target product profiles/claims, global payer evidence plans, and market access and pricing strategies. An equally important part of your role will be to lead and influence the production of scientific evidence for robust portfolio decisions, global reimbursement dossiers and reimbursement submissions to achieve market access.  

Proactively, you will predict and resolve issues that affect market access decisions and take responsibility for detailed strategic and tactical planning and implementation of payer evidence plans. By being innovative, generating novel approaches and challenging the status quo at the highest levels both internally and externally, you will deliver the strongest evidence package supporting patient access. Part of your remit will involve preparing proposals for outsourced projects and collaborating with local market affiliates to prepare evidence that satisfies payer needs in their markets. You’ll also represent health economics and payer evidence in cross-functional project teams to ensure that worldwide payer needs are reflected in our drug development programs. As part of your leadership role, you will empower other functions to support the delivery of payer strategy, anticipating and removing obstacles to their delivery and providing them with expertise, support, challenge and resource as appropriate.  

Essential Skills/Experience:

• 3-5 years of global launch experience within a health economic consultancy or pharmaceutical company (either at a marketing company/local affiliate or global level). 
• Bachelor’s degree in relevant areas, such as health economics or a related quantitative discipline. 

• Effective communication skills to different audiences, including both scientific and commercial  

• Ability to work both collaboratively and independently, understand and apply different technical approaches, and have a wide understanding of different HTA systems and their changing needs for health economic and payer evidence. 

• Applying a strategic mindset by anticipating future possibilities and translating them to breakthrough strategies as well as being resilient towards setbacks and adversity when facing difficult situations 

• Driving the publication strategy to support payer needs, generate peer-reviewed scientific publications, as well as effective communication of sophisticated ideas for use with both payers and other partners. 

Desirable Skills/Experience:

• Formal post graduate degree in health economics or a related quantitative subject area, or advanced work experience in this field 

• Payer, Health Technology Assessment, public health, or health policy experience 

• Global market access launch experience and global payer evidence development experience 

• In-depth knowledge and technical capability in health economics and payer evidence needs, and its application to pharmaceutical development at an international level, especially economic modelling, evidence synthesis, clinical trial design and analyses and other analytical techniques required to support payer needs. 

 The annual base pay for this position ranges from $ 194,147.20 - 291,220.80 USD. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered include a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Why AstraZeneca:

Here, your strategic voice shapes how science reaches people. We bring diverse experts together early to spot opportunities, learn fast, and build evidence that stands up to real-world payer scrutiny, so innovative medicines can reach millions who need them. You will join a resilient, kind, and ambitious team that pairs cutting-edge analytics with strong storytelling and negotiation, working with autonomy and deep collaboration to create sustainable access across regions and indications. This is where forward-looking minds influence the healthcare ecosystem, turning insights into action and action into impact.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Call to Action:

Step into a role where your leadership turns evidence into access—seize this opportunity to shape the future of payer strategy and patient outcomes today!

Date Posted

27-Feb-2026

Closing Date

12-Mar-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.