Global Medical Affairs Leader, Breast

Are you ready to harness evidence and scientific leadership to change how breast cancer is treated worldwide? This is a high-impact role for a strategist who can turn complex science into clear, confident action that improves patient outcomes and accelerates launches across markets.

As the accountable global medical leader for assigned breast cancer indication(s) and asset(s), you will own the Global Medical Strategy, bridge Research & Development with Commercial, and steer end-to-end launch readiness. Your work will close care gaps, promote health equity, and elevate scientific leadership—so physicians, systems, and patients can confidently adopt new standards of care.

You will lead with accountability while empowering specialized teams to execute at pace. In an open, inclusive environment that values brave, well-reasoned ideas and attentive listening, your perspective will shape decisions that matter.

Accountabilities:

• Global Medical Strategy and Launch Excellence:

• Own and deliver the Global Medical Plan for assigned breast cancer indication(s)/asset(s), setting direction, prioritizing initiatives, and making evidence-based trade-offs to maximize patient and business impact.

• Define and track clear launch and medical KPIs to diagnose progress and remove barriers to success; proactively adapt strategy to external dynamics and insights.

• Represent Global Medical on the Integrated Business Team (IBT) and Global Product Team (GPT) to shape Commercial strategy, inform development and lifecycle planning, and align on Target Product Profiles.

• Lead Medical Integrated Teams (MITs) to align global, regional, and country execution; represent Medical in Launch Readiness and Strategic Brand Reviews to elevate Medical Affairs’ role and impact.

• Influence clinical development and commercialization strategies, ensuring medical needs, evidence gaps, and companion study requirements are addressed early and decisively.

• Evidence Generation and Dissemination:

• Lead global and regional gap assessments across clinical, real-world, diagnostic, and mechanistic evidence; build integrated, cross-functional evidence plans that enable confident adoption and guideline inclusion.

• Shape the scientific and strategic design of Medical Affairs interventional studies; conceptualize and align real-world evidence programs with broader strategy; govern milestones, resources, and standards.

• Own the Global Publications Plan from late-phase development onward; ensure timely, credible, and compliant scientific communications that build trust with external experts and decision-makers.

• Champion innovative approaches—leveraging networks, novel study designs, and data-driven insights—to generate transformative evidence that changes practice.

• Confidence Building and External Engagement:

• Lead the scientific narrative from four months prior to Phase 3 investment decision, ensuring consistency across evidence, publications, congresses, and education.

• Build accountability for an Integrated Confidence Plan while partnering with centers of excellence for execution; define priority audiences, learning objectives, and delivery formats.

• Shape external engagement strategies with key experts, societies, health systems, and global organizations; gather actionable insights and actively influence to accelerate guideline adoption and health outcomes.

• Lead congress strategy end to end, including pre-congress abstracts and training, and post-congress insight synthesis and dissemination.

• Capability Building and Enterprise Leadership:

• Coach, delegate, and empower global medical teams to strengthen capabilities; model enterprise leadership that drives alignment, pace, and a culture of scientific excellence and collaboration.

Essential Skills/Experience:

• Advanced degree required (MD, PhD, PharmD, or equivalent scientific degree).

• Significant experience in Medical Affairs (~ 10 yrs) within the pharmaceutical or biotech industry, ideally at the country, Region and global level.

• Demonstrated success in leading evidence generation strategies, Medical Plans, publications, or scientific communication programs.

• Proven ability to influence senior stakeholders across Commercial, R&D, and Medical Affairs.

• Experience engaging external experts and scientific communities

Desirable Skills/Experience:

• Previous global Medical Affairs leadership experience in oncology.

• Experience leading crossfunctional teams in highly complex, multiindication environments.

• Experience navigating launch environments, new MoAs, new CDx, complex biomarker landscapes, or challenging safety profiles (aligning to GMAL complexity criteria).

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Why AstraZeneca:

Here, science and strategy meet at scale to transform cancer care. You will work with colleagues across disciplines—data, development, medical, and commercial—translating evidence into clinical practice and impacting every step of the patient journey. We move with urgency, value kindness alongside ambition, and create space for brave ideas that are heard and acted on. Surrounded by a deep pipeline and cutting-edge tools in real-world evidence and analytics, your leadership will help turn compelling data into new standards of care for people living with breast cancer.

Call to Action:

If you are ready to lead global medical strategy and deliver launches that change practice and improve lives, take the next step today and help shape the future of breast cancer treatment!

The annual base pay for this position ranges from $ 193,281 - 289,922 USD. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered include a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors

Date Posted

30-Jul-2026

Closing Date

13-Aug-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.