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Lieu: Gaithersburg, Maryland, États-Unis
ID de l'offre 12590725
Date de publication: 08/06/2019


At AstraZeneca, we are committed to advancing the science of oncology to deliver life-changing medicines to patients most in need. With a combination-focused pipeline that exploits the power of six scientific platforms (Immuno-Oncology, Tumor Drivers and Resistance, DNA Damage Response, Antibody-drug Conjugates, Cell Therapy and Epigenetics) to help address unmet clinical needs in a host of cancers, we are motivated by a dedication to the scientific discovery and collaboration that will one day help eliminate cancer as a cause of death. 

We currently have nearly 100 Phase 1, 2, 3 and Lifecycle Management Oncology projects in our robust pipeline.

We deliver the Research & Development for Oncology through our newly created Oncology R&D Unit.  This unit has responsibility for the value chain from discovery through to late-stage development, enabling rapid acceleration of promising early-stage assets and life-cycle management programs.


The Director/Product Lead will have overall leadership of global cross-functional Product Development Teams (PDT) from candidate selection through Phase III investment decision across 3 of the major platforms (IO, ADC, Cell Therapy).This individual will be accountable for the strategic leadership and execution and act as the champion for the product candidates. The successful candidate will have oncology clinical drug development experience, demonstrated leadership, and be able to critically navigate the science that underlies these programs. The candidate should be able to effectively communicate across a broad range of audiences and have an ability to clearly articulate project specific strategies as well as the overall oncology strategy.

Major Duties and Responsibilities:

·Leads product development teams responsible for novel Oncology therapies from preclinical candidate selection through proof of concept leading to Phase III investment decisions.   Accountable for the strategy and execution of a portfolio of pre-clinical and clinical stage therapies.

·Provide project leadership to create strategic and integrated product development plans which are aligned with business objectives and are differentiated from competitor products.

·Accountable for the execution of the integrated product plan to agreed scope, timelines, and budgets

·Leads and communicates the project development strategy at governance meetings, accountable for aligning with internal management and for communicating with external stakeholders.

·Leads the PDT to effectively manage/mitigate/communicate risk, make decisions, and manage conflict and change.

·Responsible for maintaining a high degree of PDT effectiveness through collaboration, influence, and, as necessary, coaching and mentoring of cross-functional team members.

Educational Requirements:

Graduate degree such as M.D.,Ph.D. or M.D./Ph.D. is required

Required Experience: 

·Industry experience in drug development including experience in early phase non-clinical and/or clinical drug development and regulatory knowledge.

·Knowledge and understanding of the Oncology therapeutic area.

·Understanding of the clinical landscape in Oncology

·Demonstrated ability to lead the development of project strategy and be accountable for project plans, timelines, progress, and outcomes.

·Demonstrated experience leading and motivating teams in a highly matrixed environment. 

·Ability to cultivate and manage internal and external cross-functional collaborations

·Strong organizational and project management skills

·Demonstrated success in influencing colleagues and senior leaders in various departments.

·Must demonstrate high integrity.

Preferred Skills: 

·Prior experience with biologics is highly desirable. 

·Experience in more than one therapeutic area as well as global late phase (II/III) drug development, regulatory submissions, and product launches is a plus.

Next Steps – Apply today!

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity.  If you know someone who would be a great fit, please share this posting with them.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.

Director, Product Development Team - Oncology Portfolio - PI
Projets, changement, amélioration de l'activité et gestion de la stratégie

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