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Associate Director, Tissue Imaging Sciences

Lieu Gaithersburg, Maryland, États-Unis Job ID R-122178 Date de publication 11/01/2021

Lab scientist with clinical  and/or research experience in immunohistochemistry and biomarker analysis.

Do you have expertise in, and passion for, immunohistochemistry and biomarker analysis? Would you like to apply your expertise to impact patients in a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the one for you!

At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.

Associate Director, Tissue Imaging Scientist, is in charge of the day-to-day operations of the Histology and Clinical Immunohistochemistry laboratory and supervision of team scientists. This includes staff development, identification and implementation of process improvements and performance management against corporate, departmental and personal goals. The Associate Director conducts scientific research as part of a team effort and demonstrates outstanding organization, technical and operational skills with the ability to lead multiple priorities effectively. The Associate Director works independently and participates effectively as part of a team.

Major Duties and Responsibilities (including supervising others):

  • Maintain a solid understanding of departmental standard operating procedures. This knowledge includes the use of specialized instrumentation, special staining techniques, quality control requirements, and preventative maintenance. Technical staining procedures include but are not limited to: routine H&E, special stains, immunofluorescence, and immunohistochemical staining.

  • Maintain up to date training in Good Laboratory Practices (GLPs) in support of toxicology studies and Good Clinical Laboratory Practices (GCLPs) for clinical trials.

  • Adhere to the highest laboratory standards including safety and company Code of Conduct.

  • Run multiple projects with high level of detail with excellent communication skills with pathologists, scientists, managers and co-workers.

  • Provide technical mentorship and oversight in the lab

  • Run departmental budget

  • Conduct research focused on the translational aspects of drug development in collaboration with supervisor and other individuals within the research department.

  • Lead all aspects of management of clinical trial samples and staining

  • Find opportunities and lead team in the process of improving initiatives and implementing action plans.

  • Ensure accurate management of research, pre-clinical and clinical human tissue following company’s HBS guidelines.

  • Supervisory duties include full range of recruitment and performance evaluation activities and individual staff development

  • Ensure staff are trained and proficient

  • Proactive integration with internal and external groups and suppliers. Collaborate with counterparts globally to harmonize standard methodologies across sites to ensure alignment.

  • Continually enhance slide quality as well as the efficiency of the personnel and laboratory areas.

  • Handle departmental workload and prioritization. Coordinates the daily/weekly activities of the team.

  • Resolve problems and notify manager of resolutions, as appropriate

  • Ensure that all employees follow all company and departmental policies; initiate performance improvement with employees as needed.

  • Participate in company meetings and conduct department meetings routinely

  • Maintain equipment and instruments in good operating condition’ recognize any malfunctions and troubleshoot.

  • Perform others duties as assigned.

Education Required:

Minimum MS degree, PhD preferred, with 1-3 years’ experience preferred.

Experience Required:

  • Experience in routine histology/microtomy and IHC

  • Leadership skills

  • Shown project management skills

  • Basic understanding of drug development process for biologics

  • Basic understanding of immunology

  • Basic understanding of pharmacokinetics and PK/PD relationships

Level of Supervision Required:

High level of independence; required to supervise laboratory functions and direct reports with minimal oversight from manager.

Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.

So, what’s next? If you are ready to bring new ideas and fresh thinking to the table, apply today!


Where can I find out More?

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

AstraZeneca embraces diversity and equality of opportunity.  We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.  We believe that the more inclusive we are, the better our work will be.  We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.  We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

AstraZeneca has taken critical steps to protecting colleagues, loved ones, and patients from COVID-19 and its variants.  COVID-19 vaccination is required for all US employees, and weekly PCR COVID-19 testing is required for those who are unvaccinated or have an approved accommodation.



AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

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