Analytical Scientist – ADC Characterization

Analytical Scientist – ADC Characterization

Gaithersburg, MD

We are seeking a highly motivated Analytical Scientist with a strong background in the characterization of antibody-drug conjugates (ADCs). As part of our dynamic team, you will play a crucial role in supporting the development and optimization of ADCs for various therapeutic areas. Join us in pushing the boundaries of science to transform the lives of patients living with cancer.

Accountabilities

• Analytical Characterization: Conduct comprehensive characterization of ADCs using a variety of analytical techniques such as HIC-HPLC, SEC, LC-MS, IEX, and RP-HPLC.
• Method Development: Develop, validate, and optimize analytical methods for the characterization of ADCs.
• Data Analysis: Analyze and interpret complex data, ensuring accurate and reliable results to support ADC development.
• Documentation: Maintain detailed and organized records of experiments, methodologies, and results in accordance with regulatory standards.
• Collaboration: Work collaboratively with a team of scientists across multiple disciplines to ensure timely progress in research projects and contribute to the overall success of the program.
• Presentation: Effectively communicate findings and present complex scientific data to cross-functional teams and senior management.

Essential Skills/Experience

• Masters in Chemistry, Biochemistry, Chemical Biology, or a related field with 3+ years of relevant industrial experience.
• Analytical Techniques: Hands-on experience with analytical techniques such as Hydrophobic Interaction Chromatography (HIC)-HPLC, Size Exclusion Chromatography (SEC), Liquid Chromatography–Mass Spectrometry (LC-MS), Ion-Exchange (IEX), and Reversed Phase (RP)-HPLC.
• Method Development: Proven experience in developing and validating analytical methods for protein and conjugate characterization.
• Data Analysis: Strong skills in data analysis and interpretation, with proficiency in relevant software tools.
• Problem-Solving: Demonstrated ability to troubleshoot and solve complex analytical problems.
• Documentation: Excellent attention to detail and experience in maintaining accurate laboratory records.
• Communication: Strong written and verbal communication skills, with the ability to present data and findings clearly to a variety of audiences.

Desirable Skills/Experience

• Mass Spectrometry: Experience with mass spectrometry for ADC characterization is a plus.
• Regulatory Knowledge: Familiarity with regulatory requirements and guidelines for biopharmaceutical analysis.
• Team Collaboration: Proven ability to work effectively in a collaborative, cross-functional team environment.

At AstraZeneca, we are dedicated to following the science. Our team is driven by curiosity, passion, and determination to change the practice of medicine in Oncology. With one of the broadest and deepest Oncology pipelines in the industry, we offer numerous opportunities to work with new and novel drugs. We foster a collaborative environment where diverse knowledge from across the business and external partners is leveraged to tackle the toughest medical challenges. Empowered by our collective courage and curiosity, we take smart risks, challenge norms, and learn from failures. Join us at the forefront of applying science to studies and using innovative approaches to create new possibilities.

About Our Gaithersburg Oncology Hub

Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We are dedicated to creating a culture of inclusion and collaboration.

The Gaithersburg site offers a variety of amenities to help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center, game rooms, community garden and more. This is where you’ll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams.

So, what’s next?

Join us at AstraZeneca and make a meaningful difference for patients around the world!

If you’re curious to know more, please contact Bobbi Poole, our Talent Acquisition Partner.

Closing Date: December 16, 2024

Competitive remuneration and benefits apply

We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package.

Where can I find out more-

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

The annual base pay (or hourly rate of compensation) for this position ranges from $87,200 to $130,800. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.