Study Contracts Manager

Contracts Manager

This Contracts Manager role focuses on coordinating key aspects of clinical trials, working as part of a clinical delivery team to provide support, guidance and advice at a local level. The position develops and refines tools and processes to identify improvements and secure business continuity for oncology study delivery. It involves solving complex problems across a range of studies while leading the clinical agreement and site-level budget negotiation process to ensure ethical, fair and compliant practices in developing, negotiating and executing clinical agreements and investigator budgets. The role provides leadership, direction and guidance through process improvement, interactive communication and stakeholder management, requiring a high level of engagement to set clear direction for study teams and external institutions.

Accountabilities

Lead the development and negotiation of clinical site budgets, in collaboration with the LSAD, based on Fair Market Value, using historical data, negotiation techniques and standard-of-care considerations to support oncology trial delivery while optimising cost savings.

Negotiate agreement language with clinical study sites to secure a shared understanding of deliverables, timelines for study start-up and financial obligations.

Produce clinical site budgets and appropriate payment schedules, aligned with protocol requirements and company policies and guidelines, for the Clinical Delivery Team.

Identify and apply the correct agreement templates to initiate negotiations, acting as the primary point of contact with Legal where needed to ensure contract integrity.

Drive site start-up performance by striving to execute Clinical Study Agreements within agreed KPIs, maintaining up-to-date status on agreements, budgets, issues and communications with internal and external stakeholders.

Participate actively in project team meetings, ensuring final contract documents reflect negotiated terms and are accurately captured in contracting systems.

Contribute to the set-up and execution of master confidentiality agreements and confidentiality agreements with key partner sites, supporting internal and external audits and any litigation activities.

Negotiate appropriate terms and conditions of Informed Consent Forms and other clinical agreements and associated documents, processing agreement requests and identifying the correct legal entity and template.

Approve Clinical Study Agreements with final signature in line with Delegation of Authority, negotiate common contractual issues related to standard templates, and manage contract amendments from initiation through completion.

Work as a member of the Local Study Team, partnering with study teams to determine priorities that meet timelines and Site Initiation Visit dates, serving as a liaison between legal and clinical trial teams.

Negotiate master templates and rate cards with preferred or notable institutions, including creating, implementing and following specific partnering MSAs with key oncology institutions.

Act as a subject matter expert in contracts and negotiation, balancing external business exposure with internal policies and regulations, demonstrating how contractual terms add value for internal and external customers.

Apply detailed knowledge of contracting principles, processes and budget development, communicating confidently to influence stakeholders and showing how contracting and budget processes support project management practices such as schedule and cost forecasting and risk management.

Maintain accurate knowledge of regulations and policies to sustain and enhance the effectiveness of Clinical Study Agreement and Grant Management processes, working within defined processes and ensuring compliance with the company Code of Conduct and policies on people, finance, technology, security and Safety, Health and Environment.

Ensure timely customisation and completion of CSAs for designated studies, contribute to training and mentoring new members of the local Study Delivery Team in line with ICH/GCP and procedural documents, ensure readiness of study documents for final archiving and Trial Master File completion, and drive process improvements, knowledge transfer and best practice sharing.

Essential Skills/Experience

Bachelor’s degree in relevant discipline  
Experience of Study Management within a pharmaceutical or clinical background  
Knowledge of relevant legislation and new developments in the area of Clinical Development and Study Management  

Desirable Skills/Experience

Advanced degree within the field  
Professional certification  
Understanding of multiple aspects within Study Management  

At AstraZeneca, work centres on following the science, pioneering new frontiers in oncology and turning bold ideas into tangible advances for patients. Teams operate in an environment built on courage, curiosity and collaboration, where cutting-edge science meets the latest technology to push an innovative pipeline forward. Colleagues are empowered to lead at every level, take smart risks and work seamlessly with an unrivalled global network of academic partners and medical centres. With strong investment, clear ambition and a shared commitment to transform outcomes for people living with cancer, this is a place to build a meaningful career while contributing to research that aims to eliminate cancer as a cause of death.

Ready to shape the future of oncology trials through impactful contracting and negotiation? Apply now!

Date Posted

15-abr.-2026

Closing Date

25-abr.-2026

AstraZeneca embraces diversity and equality of opportunity.  We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.  We believe that the more inclusive we are, the better our work will be.  We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.  We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.