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Senior Global Medical Affairs Leader - Breast

Lieu Cambridge, Angleterre, Royaume-Uni Job ID R-178469 Date de publication 02/13/2024

Join a place that’s working to fundamentally change the way cancer is treated. Evolving to an outcomes-based model – we go beyond treatment to shape the cancer care environment and transform the whole patient experience. We work holistically, from early diagnosis to survivorship, ensuring no patient is left behind. Each of us believes that by delivering earlier stage interventions with curative possibilities and championing the development of precision combinations, we can transform the lives of patients living with cancer across the world.

Reporting to the Head of Small Molecules, Breast Cancer Franchise, the Senior Global Medical Affairs Leader (GMAL) plays a pivotal role in channelling our scientific capabilities to make a positive impact on changing patients’ lives.

As an experienced medical leader with clinical or scientific experience in oncology, the position holder will be responsible for the medical strategy development and execution of key deliverables to develop further multiple identified positive indications, build the associated medical plans to support their development further, leading to medical strategies to enable the launch of assets/brands and find opportunities to extend the lifecycle management of brands globally.

The position holder will work across multiple internal and external collaborators and will contribute to key decisions in regards to brand marketing direction, as well as, where applicable, research and development direction. As a member of the Global Medical Senior Leadership Team, the position holder will contribute significantly beyond their asset remit to setting and delivery of wider medical strategic direction for the tumor area

Typical accountabilities

·Leads on the global strategy from Oncology brand medical perspective across multiple indications within the Tumor area

·Will work across Tumor areas at a brand/asset level to ensure tumor and brand strategies align to ensure the maximum medical impact

·Will be a key member of the Tumor Global Medical Senior Leadership Team, shaping tumor level strategy and priorities

·Responsible for ensuring brands/multiple indications within area of responsibility, have strategic medical plans in place to ensure appropriate financial and resource planning both within the direct remit of accountability but also ensuring broader resources across the medical organisation (globally and in market) are in place. Strategic medical plans will ladder up to overarching brand strategic plans.

·Will have Medical accountability for strategic external partnerships and alliances management for the development and launch of brands

·Leads and is accountable for the development and execution of the asset specific medical tactical plan aligned to strategy including evidence generation, scientific communications, interactions with global external experts, diagnostics strategy and patient centric activities

·Is accountable for setting the Real World Evidence and External KEE engagement strategies to establish confidence in our brands and their impact on patients

·Leads the Tumor/Asset Global Medical Team (GMT) engaging and influencing in market medical teams and of prioritized launch market teams to ensure that relevant global and in market insights are used to inform product development, brand strategies and launch plans

·If appointed, will represent medical at a Global Product Team level on key decisions regarding Asset direction/strategy and prioritisation, will act as both a key influencer and decision maker

·Will engage with multiple senior stakeholders including SET level executives to provide insights, data, launch plans and recommendations that will influence global brand decisions

·Will represent AstraZeneca at a Global level as key external events, congresses, scientific symposia’s etc and will liaise with and external stakeholders to enhance the scientific and clinical understanding of brand/asset in relation to the tumor/tumor type and clinical landscape

·Partners closely with colleagues in the Markets, OBU-Medical (Publications, Global Medical Information, RWE, Medical Excellence), Late and Early-Stage Development (Oncology R&D), Global Marketing, Global Strategy, Regulatory Affairs, Payer, Health Outcomes and other key functions, and helps build alignment on key initiatives including optimal approach to data generation, communication and supporting access

·Act as (or delegate to another GMAL on the team) Medical Study lead for GMA-sponsored Tumor/brand/asset-multi-indication cancer studies

·Providing medical leadership to support to Health Authority (HA) and Investigational Review Board (IRB) regulatory interactions and to Clinical Research Organization (CRO) in charge of study execution

·Leads or coordinates a diverse range of initiatives to improve decision making within the marketing, research and development function and other areas that may be applicable. Accountable for building and lead an outstanding team, attracting, engaging and retaining talent for the future, by fostering a culture of inclusion

·Provides leadership, coaching, feedforward to teams and individuals to upskill and develop future capabilities in line with AstraZeneca’s commitment to a culture of performance development and lifelong learning

·Ensures that all Medical and business activities are carried out in compliance with AZ standards, standard operating procedures and external regulations

Essential requirements

·Minimum of Master’s degree in a scientific discipline or equivalent medical/scientific qualifications and/or significant industry and/or therapeutic experience(MD preferred)

·Minimum 8 years of senior leadership/specialized experience within pharma/life sciences and/or medical experience (e.g., significant clinical/academic/medical affairs agency roles/organisations)

·Able to evaluate, interpret and present highly complex data for a series of studies

·Ability to lead cross functional working groups and teams with a complex matrix organisation

·Significant understanding of the overall drug development process and branding medical drugs

·Extensive experience in stakeholder management & situational leadership

·Experience of financial and resource planning and management is essential

·Ability and track record of utilising data and insights to prioritise medical plans and studies

·Ability to influence strategically and persuade tactfully, to obtain desired outcomes while maintaining effective, positive organisational relationships

·Excellent presentation and communication skills with the ability to meet the needs of scientific, commercial needs

Desirable requirements

·Experience in drug development and in oncology (strong preference)

·Breast Cancer experience

·Country launch experience as well as global experience

·Alliance management experience would be advantageous



AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

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