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Associate Director, Real World Data Science - Evergreen

Lieu Cambridge, Angleterre, Royaume-Uni Job ID R-213003 Date de publication 11/12/2024

BioPharmaceuticals Medical (BPM) ensures the best patient outcomes by providing healthcare decision-makers around the world with the evidence and confidence they need on AstraZeneca therapies. BPM provides medical leadership with market participation and connectivity while also impacting the life cycle planning and execution of all our products. BPM aims to lead AstraZeneca in achieving scientific leadership and keeping patients at the core of everything we do.

BioPharmaceuticals Medical Evidence is accountable for delivering global strategic studies required to generate the evidence to build confidence in AstraZeneca therapies. The Associate Director, Real World Data Science role reports directly to the Senior Director, RWD Science and will have a proven track record of delivering value through using routinely collected data from healthcare settings or observational studies. This role will collaborate with colleagues in epidemiology, statistics, and health economics to shape the RWD science delivery of medical and payer evidence studies.

Accountabilities

- Deliver/Implement advanced secondary analyses of data from EMR, claims, and primary observational data required across Therapeutic Area (TA) RWE strategies
- Provide expert scientific guidance on the application of real-world evidence and observational research data to address issues and interests across the Biopharmaceuticals business units
- Provide expert technical input, options, and directions to strategic decisions made by AZ observational study teams on study design, data partner selection, and standard processes in RWD utilization
- Mentor/coach and support the education and technical training of other data scientists
- Provide support for strategic decisions on AZ Medical Evidence and Observational Research external collaborations in the US and other markets
- Collaborate with internal teams to evaluate and assess strengths and weaknesses of external RWD sources, and potential partners for advancing the data strategy for specific therapeutic areas
- Maintain a strong insight into the capabilities of potential external partners in RWE, especially for US and emerging markets.
- Promote standard process in RWD Science across multiple domains, and/or partner groups

Essential Skills/Experience

- PhD or MS or equivalent experience in statistics, mathematicadvanced degree or equivalent experience or other advanced degree in life sciences + relevant industry experience
- Experience in real-world evidence and familiarity with health economics/epidemiology, and quantitative science such as health outcome modelling
- Hands-on experience with EMR/Health IT, disease registries, and/or insurance claims databases
- Experience within clinical data standards, medical terminologies and controlled vocabularies used in healthcare data and ontologies (ICD9/10/SNOMED)
- Experience in supporting pharmacoepidemiology studies with consistent record of advancing approaches with statistics/machine learning/data science
- Ability to lead & handle multi-disciplinary data science projects
- Familiarity in Statistical Analysis Plan (SAP) generation and execution for observational studies
- Proficient in SQL 
- Proficient in R/Python

Desirable Skills/Experience

- Demonstrated ability to build long-term relationships with customers, understand relevant scientific/business challenges at a deep level and translate into a programme of data science activities to deliver value to the business
- Experience in advanced visualisation and visual analytics of routinely collected healthcare data
- Experience in the application of pharmacovigilance from RWD
- Experience working in a global organization and delivering global solutions

At AstraZeneca, we are dedicated to pushing the boundaries of science to deliver life-changing medicines. Our inclusive culture fosters innovation by connecting different perspectives to generate new opportunities. We are committed to lifelong learning, growth, and development for all our employees. Here, you will find a dynamic environment where challenging work goes hand in hand with development opportunities.

Join us on our journey to pioneer the future of healthcare. Apply now!



AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

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