Global Commercial Director Weight Management, CVRM

At AstraZeneca we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. We’re focused on the potential of science to address the unmet needs of patients around the world. We commit to those areas where we think we can really change the course of medicine and bring big new ideas to life.

Within BBU CVRM, we have established a new VP commercial area focusing on Weight Management and T2D. Our ambition is to deliver a portfolio of simple, scalable, and sustainable solutions that improve health and wellbeing, reduce cardiometabolic risk and protect organs for people living with diabetes, overweight, and/or obesity.

As Global Commercial Director, Weight Management, you will lead the launch strategy for a new asset in its initial weight management indication — a first-in-class opportunity to craft how AstraZeneca shows up in a rapidly evolving therapeutic category. This is a pivotal pre-launch role focused on shaping a new market space, grounded in patient insights, cultural understanding, and strategic storytelling.

The role reports to the Global Commercial Head Weight Management.

Key Responsibilities

• Develop and lead a global commercialization strategy for the weight management — defining market segmentation, positioning, and launch sequencing.

• Translate strategic vision into an actionable global pre-launch roadmap with clear brand pillars and stakeholder engagement priorities.

• Design a differentiated brand story that balances scientific credibility with emotional resonance for patients, HCPs, and advocacy groups.

• Partner with Global Insights, Analytics, and Patient Experience teams to uncover deep behavioral, emotional, and cultural insights driving obesity care.

• Shape the ecosystem around obesity through disease education, early access, and policy-shaping initiatives.

• Build validation loops through advisory boards, digital ethnography, and patient co-creation sessions.

• Collaborate across Global Medical, Access, R&D, and Regional teams to ensure commercial readiness and alignment on value narrative, TPP, and launch framework.

• Define key pre-launch milestones (e.g., value proposition testing, access readiness, digital engagement planning).

• Ensure knowledge transfer and capability-building across first-wave markets.

• Oversee development of global brand identity, naming, and creative platform for AZD5004 in weight management.

• Lead agency partnerships to deliver compelling disease awareness and pre-launch content.

• Embed digital and omnichannel strategies that reflect evolving patient and HCP journeys.

• Serve as a key member of the Global Commercial Leadership Team for CVRM Weight Management.

• Champion a new category narrative that challenges stigma and redefines how people think about obesity as a chronic disease.

• Present GTM strategy and investment recommendations to senior governance and cross-functional boards.

Essential Skills / Experience

• Bachelor’s degree; MBA or advanced degree preferred.

• 10+ years of commercial or strategic marketing experience in biopharma, ideally in pre-launch settings.

• Demonstrated experience in insight generation, positioning, and market shaping.

• Proven success in driving cross-functional alignment and influencing senior stakeholders.

• Strong working knowledge of forecasting, market research, actionable insight generation, and competitive landscape analysis and interpretation

• Experience in obesity, metabolic, or consumer health strongly preferred.

• High personal drive to find new solutions and challenge the broader organisation to deliver

Desirable Skills

• Commercial/marketing role in US or other large Market with Launch Experience

• Previous experience in a Global role

• Experience establishing or expanding a therapeutic category.

• Familiarity with omnichannel engagement and behavioral science-based marketing.

• Strong understanding of pricing and access dynamics in obesity market.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

AstraZeneca offers an environment where diversity is our strength, reflecting the variety of patients we serve. Here, you'll find a place for continuous learning, exchanging knowledge, and building best practices to grow your career. With a fusion of support, trust, and agility, you'll be encouraged to bring your whole self to work and embrace all the investment, feedback, and ample opportunities on offer. It's an exciting time for our team as we redefine the future of healthcare.

Ready to jump in and be part of something extraordinary? Apply now and take the next step in your career journey with AstraZeneca!

The annual base pay for this position ranges from $229,303 to $343,955. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.  In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. ​

Date Posted

06-Nov-2025

Closing Date

19-Nov-2025

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.