Senior Manager Genomics Operations

AtAstraZeneca, we work together across global boundaries to make an impact and find answers to challenges. We do this with the utmost integrity even in the mostdifficult situationsbecause we are committed to doing the right thing. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people’s exceptional skills with those of people from all over the globe.

Oncology Translational Medicine Genomics 

The Translational Medicine function exists within Oncology R&D to ensure effective and strategic biomarker studies for oncology project teams. Closely interacting with the pre-clinical Discovery, Early Clinical Development, and Precision Medicine &Biosamplesdiagnostics functions, Translational Medicine is the single point of accountability for delivery of robust,scientifically-drivenbiomarkers to all Oncology project teams, providing feasibility assessments, technical validation, centralized biomarker analysis capability for clinical samples, delivery of translational science research and early clinical phase engagement.

The Global Genomics team within Translational Medicine functionleveragesNext Generation Sequencing (NGS) and other advanced technologies to match the right patient to the right drug and support precision oncology approaches for the AZ Oncology pipeline.

Major Responsibilities and Accountabilities

Thisposition will focus on3core areas:

Operations Management (e.g.,Financialmanagement,Purchasing, Non-LaboratorySupplier & Logistics, etc.)

Financial Management:

Owner ofmonthly accruals,functionalbudget, providefinancial oversighttotheTM Genomicsteam

Contracting and Management of Vendor Activities:

• Generate, manage, track and drive to closure all POsandinvoicesfor commercial sample and non-CapExpurchases

• Develop,manageand execute vendor contracts for technical evaluations 

• Supplier setup, request for quote, purchase order creation, reconciliations of invoicing, and release of payments

• Manage specimen vendors and other suppliers asrequired

• Coordination of shipping and receiving of critical R&D itemsas needed

Business OperationsManagement & Coordination

• Lead, support and coordinate business improvement projects and investigations forTMGenomics Leadership teamfor continuous department improvements and day-to-day operations. 

• Examples: SOP enhancements, ITinitiatives,processautomationsand other projects that improve R&D throughput andreducedthe administrativelogisticsonlaboratorystaff.

• Assistinestablishingand documentingoperational processesand proceduresto provide operational support to research labs

• Act as escalation point to manage issues related to specimen and results management

• Identifyprocess gaps inbusiness processesand make recommendations for continuous improvement with a focus onresource usageand turn-around time

• Support management and research labs in strategic, operational planning (KPIs) and execution in company intended direction

• Develop andmaintainbusiness analyticsand agentic tools to enhance operational excellence

TM Genomicsleadershipsupport

TM Genomics Leadership TeamSupport:

• Provide advancedassistanceto theleadership teamby performing various complex business support functions, typically of a confidential nature

• Assistwith budgeting process which includes gathering data, data input, and financial analysis

• Manage and tracksensitive and/or critical information, files, records, and reports

Essential for the role

• B.A,B.S. inBiotechnology,BiologyorManagement,orrelateddegree with3+ years of business/operationsexperiment in a pharmaceutical, diagnostics or related research setting

• Experience withOncology,Next Generation Sequencing,TranslationalMedicine orearly stageclinical trials 

• Experience withfinancial managementand operating budgets

• Familiarity with NDA, MSA, SOW development and IT security assessments

• Demonstrated success in completing on time medium/ large business projects with attention to details and complexity

• Demonstrated skills interacting with diverse stakeholder groups including senior leadership, scientific strategists, bioinformaticians, lab scientists and business operations team membersleveraginga strong scientific background

• Demonstrated ability to lead, communicate, and influence effectively at all levels across the organization

• Experienced in quickly building positive and trusting relationships

• Ability to effectively implement continuous improvements to increase efficiency and promote simplification whilemaintainingproject schedules

• Strongteamleadership skills,oral and written communicationskillsand meeting facilitation skills with the ability to work with others to achieve objectives

Desirable for the role

• Advanceddegree (PhDor MS) in Biology, Genetics, Oncology,Bioinformatics)

• Working knowledge of document management applications and study planning tools (eg.Planisware,SmartSheet,MS Project,Tableau, Power BI,Power Query,Veeva,Copilot Studio, Power Automate,Miro, Office Timeline,Confluenceand/or Jira, etc.) andMicrosoft tools, such as MS Project, Outlook, Word, Excel, Power Point and Visio

• Experience withfinancialreporting, contractexecution, vendoronboardinganddiligence 

• Ability to multi-task in a fast-paced environment with changing priorities, comfort with ambiguity

• Interest in KPIand complex dashboarddevelopmentprovidingbusiness insightsas well as IT/AI platforms and systems

• Proventrack recordof relationship management, influencing and negotiating across a global organization with complex groups and multiple geographies

• A sense of ownership and enterprise leadership to deliver high quality solutions that solve business problems

About AstraZeneca inBarcelona

TheBarcelonasite is situated within a biopharma cluster of research institutions, medical centers, pharmaceuticalcompaniesand startups.

OurBarcelonasitedevelopslife-changing medicines for people around the world. We believe employeesbenefitfrom being challenged and inspired at work. We are dedicated to crafting a culture of inclusion and collaboration.