Principal Programmer - Data Science Systems

Job Title: Principal Programmer - Data Science Systems

• Work Location: Manyata Tech Park, Bangalore, India

• Work Schedule: Three days on-site, two days remote (3/2)

• Career Level: E – Individual Contributor position.
  

Introduction to role:

Are you ready to make a difference in the world of data science? As a Principal Programmer in Data Science Systems, you'll be at the forefront of developing ground breaking applications and methodologies within the Quantitative Sciences organization. Your strong technical, organizational, and project management skills will guide internal and external collaborators in implementing software tools and technologies that redefine clinical study development and execution. Collaborate with leaders in Programming, Biostatistics, Epidemiology, and Medical Writing to identify technology needs and streamline practices. Dive into the world of data science technologies to improve clinical analyses and operations.

Accountabilities:

• Develop, maintain, implement, and manage applications using data science software within the QS organization.

• Coordinate project direction for internal and external projects in tool development and deployment.

• Lead life cycles of data science services including versioning, training, and documentation.

• Review and supervise change requests for data science applications.

• Find opportunities for new data science technologies to improve QS operations.

• Research alternative solutions to current problems with recommendations for efficient solutions.

• Implement standard methodologies in software development to improve quality and efficiency.

• Develop Standard Operating Procedures for regulatory deliverables using data science technologies.

• Serve as a liaison with Alexion IT for tool development using data science technologies.

• Represent QS Statistical Programming in cross-functional projects for innovative solutions.

• Act as a subject matter authority on data science technologies during audits.

• Provide training to DOQS and contracted staff for applications developed with data science technologies.

• Lead department data science environment for clinical study data analysis.

• Coordinate aspects of applications developed with data science technologies including licenses and user accounts.

• Serve as a statistical lead programmer contributing to project programming efforts.

• Develop and validate programming specifications for analysis datasets using Alexion standards.

• Independently develop programs generating analysis datasets based on specifications.

• Develop programming specifications for protocol-specific safety and efficacy tables.

• Independently develop programs generating safety and efficacy tables using Alexion specifications.

• Represent Alexion at conferences to present data science technology trends.

Crucial Skills/Experience:

• BS/MS/MA in Statistics, Biostatistics, Computer Science, Data Science, Mathematics or related area. Advanced degree or equivalent experience with strong analytical skills is preferred.

• 6+ years’ data science or statistical programming experience in the pharmaceutical, biotech or CRO Industry.

• Some proven experience and solid understanding of data science technologies such as R, Python, C++, C#, Java or AI/machine learning.

• 2+ years project management experience in the biotech or pharmaceutical industry is required.

• Work experience and validated skills in the use of R or SAS within a Statistical Programming environment to develop and validate analysis datasets, tables, listings, and figures/graphs is required.

• Confirmed abilities to lead and handle cross-functional projects from concept to completion.

• Proficiency in the roles and responsibilities of all related subject areas within the QS department, with a focus on Biostatistics, Clinical Data Management, Epidemiology, and Medical Writing.

• Strong verbal and written communication skills with ability to clearly and effectively present information.

• Strong knowledge and understanding of software development with familiarity of a general programming language (i.e. C++, Java, Python, etc.), version control (Git), CI/CD platforms, open-source and private APIs, and various SDE tools.

• Experience with CDISC SDTM and ADaM models and clinical analysis reporting is preferred.

• Knowledge of clinical database design specifically electronic data capture and management, and the implementation of external data sources is preferred.

Advanced experience with:

• Constructing technical programming specifications.

• Relational Databases.

• Good Clinical Practices.

• Good Programming Practices.

• 21CFR Part 11 Standards.

• Crafting all files necessary to support an electronic submission in the eCTD format.
  

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

At AstraZeneca's Alexion division, we champion diversity and foster an energizing culture where new ideas thrive. Our commitment to inclusion ensures that life-changing innovations can come from anywhere. We celebrate each other's successes and take pride in giving back to our communities. Here, your career is more than just a path; it's a journey to making a difference where it truly counts.

Ready to make a difference? Apply now to join our team!

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, gender expression, sexual orientation, age, marital status, veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.